Other manifestations may include alterations. Bloody diarrhea with pallor and petechiae should raise concern about the possibility of hemolytic uremic syndrome Thrombotic Thrombocytopenic Purpura (TTP) Thrombotic thrombocytopenic purpura (TTP) is an acute, fulminant disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia. ![]() Symptoms, usually severe, include headache, nausea, vomiting, photophobia. Any child presenting with fever and petechiae or purpura must be evaluated carefully for the possibility of meningococcemia Meningococcal Diseases Meningococci ( Neisseria meningitidis) are gram-negative diplococci that cause meningitis and meningococcemia. read more, staphylococcal scalded skin syndrome, and Stevens-Johnson syndrome. It is characterized by fever, cough, coryza, conjunctivitis, an enanthem (Koplik spots) on the oral mucosa. read more, measles Measles Measles is a highly contagious viral infection that is most common among children. Conjunctival inflammation may occur in Kawasaki disease Kawasaki Disease Kawasaki disease is a vasculitis, sometimes involving the coronary arteries, that tends to occur in infants and children between the ages of 1 year and 8 years. read more and are considered dermatologic emergencies. Drugs, especially sulfa drugs, antiseizure drugs, and antibiotics, are the most common. read more or Stevens-Johnson syndrome Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) Stevens-Johnson syndrome and toxic epidermal necrolysis are severe cutaneous hypersensitivity reactions. ![]() Symptoms are widespread bullae with epidermal sloughing. Infants and children are most susceptible. ![]() read more are usually self-limited maculopapular exanthems, but sometimes more serious reactions occur.īullae and/or sloughing suggest staphylococcal scalded skin syndrome Staphylococcal Scalded Skin Syndrome Staphylococcal scalded skin syndrome is an acute epidermolysis caused by a staphylococcal toxin. The most serious of these are discussed elsewhere in THE MANUAL and include Stevens-Johnson syndrome and toxic epidermal necrolysis, hypersensitivity. Cutaneous drug reactions Drug Eruptions and Reactions Drugs can cause multiple skin eruptions and reactions. ![]() read more ) have a fairly typical appearance and clinical manifestation others are nonspecific. In children, it causes mild constitutional symptoms and a blotchy or maculopapular rash beginning on the cheeks and. read more, both of which are currently uncommon because of vaccination but should be considered in unvaccinated children erythema infectiosum Erythema Infectiosum (Parvovirus B19 Infection) Erythema infectiosum is caused by acute infection with human parvovirus B19. read more and measles Measles Measles is a highly contagious viral infection that is most common among children. It usually begins with mild constitutional symptoms that are followed. Some (eg, chickenpox Chickenpox Chickenpox is an acute, systemic, usually childhood infection caused by the varicella-zoster virus (human herpesvirus type 3).
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